COVID-19 Vaccination Adverse Reactions (CVAR) Dataset

COVID-19 Vaccination Adverse Reactions (CVAR) Dataset#

Last modified: 15 Dec 2025

Adverse reactions to vaccinations against SARS-CoV-2 in England.

1. Summary#

Data were collected about people in England who had an adverse reaction to a SARS-CoV-2 vaccination within the first 15 minutes after administration of the vaccine. Data collected include demographic information, vaccination details, vaccine batch details and information about the adverse reaction.

Dataset Descriptor Dataset-specific Information
Name of Dataset in TRE NHSE_CVAR
Citation (APA) Data Services, NHS England (NHSE). (2023). NHS England: COVID-19 Vaccination Adverse Reactions. UK Longitudinal Linkage Collaboration (UK LLC). https://doi.org/10.71760/ukllc-dataset-00381-02
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Series NHS England
Owner NHS England
Copyright Copyright © (2026), NHS England. Data re-used with the permission of NHS England. All rights reserved.
Temporal Coverage in the TRE 12/2020 - ongoing
Geographical Coverage England
Participant Count 46
Number of Variables 31
Number of Observations 100
Key Link https://digital.nhs.uk/services/data-access-request-service-dars/dars-products-and-services/data-set-catalogue/covid-19-vaccination-adverse-reactions
Keywords COVID-19, Vaccination, Adverse reaction
Latest Extract Date 2024-04-26
Specific Restrictions to Data Use Research must be related to COVID-19. For examples of research purposes acceptable to NHS England see the COVID-19 Public Health Directions 2020: https://digital.nhs.uk/about-nhs-digital/corporate-information-and-documents/directions-and-data-provision-notices/secretary-of-state-directions/covid-19-public-health-directions-2020
Build a Data Request https://explore.ukllc.ac.uk/

2. Metrics#

Click on the plus sign to see the number of participants represented in each dataset.

Table 2: Participants from each LPS represented in the CVAR dataset in the UK LLC TRE. Note: Individual cohort counts of less than 10 are suppressed to <10 and excluded from total participant counts for datasets.

3. Version History#

Version 1 2
Version Date 21 Dec 2022 13 Apr 2023
Number of Variables 30 31
Number of Observations 98 100
DOI 10.71760/ukllc-dataset-00381-01 10.71760/ukllc-dataset-00381-02
Change Log 10.71760/ukllc-dataset-00381-01/activities 10.71760/ukllc-dataset-00381-02/activities

4. Documentation#

We are currently building a documentation storage system which will host useful documents related to datasets and data owners. We will surface these documents on Guidebook.

5. Useful Syntax#

Below we will include syntax that may be helpful to other researchers in the UK LLC TRE. For longer scripts, we will include a snippet of the code plus a link to the UK LLC GitHub repository where you can find the full scripts.