Enzyme-linked Immunosorbent Assay (IELISA) Dataset#

1. Summary#

The information below is retrieved from the Health Data Gateway API developed by NHS England, with additional fields added by UK LLC (indicated by italics). This dataset is also known as the Covid-19 UK Non-hospital Antibody Testing Results dataset.

# define target dataset to document
schema = 'nhsd'
table = 'IELISA'
version = 'v0003'
# import functions from script helper
import sys
script_fp = "../../../../scripts/"
sys.path.insert(0, script_fp)
from data_doc_helper import DocHelper
# create instance
document = DocHelper(schema, table, version, script_fp)
# markdown/code hybrid cell module requirement
from IPython.display import display, Markdown
# get api data
dataset = document.get_api_data()
display(Markdown("**NHS England title of dataset:** "+dataset['datasetfields']['metadataquality']['title']))
display(Markdown("***Dataset name in UK LLC TRE:*** *nhsd.IELISA*"))  
display(Markdown("**Short abstract:** "+dataset['datasetfields']['abstract']))
display(Markdown("***Extended abstract:*** *Also referred to as the Covid-19 UK Non-hospital Antibody Testing Results dataset, IElisa documents individuals who have had a finger prick test for antibodies following a COVID-19 infection (i.e. Pillar 3). The dataset is UK wide and includes demographic and diagnostic information.*"))
display(Markdown("**Geographical coverage:** "+dataset['datasetfields']['geographicCoverage'][0]))
display(Markdown("**Temporal coverage:** "+dataset['datasetfields']['datasetStartDate']))
display(Markdown("***Data available in UK LLC TRE from:*** *01/09/2020 onwards*"))
display(Markdown("**Typical age range:** "+dataset['datasetfields']['ageBand']))
display(Markdown("**Collection situation:** "+dataset['datasetv2']['provenance']['origin']['collectionSituation'][0]))
display(Markdown("**Purpose:** "+dataset['datasetv2']['provenance']['origin']['purpose'][0]))
display(Markdown("**Source:** "+dataset['datasetv2']['provenance']['origin']['source'][0]))
display(Markdown("**Pathway:** "+dataset['datasetv2']['coverage']['pathway']))
display(Markdown("***Information collected:*** *Demographic and diagnostic information.*"))  
display(Markdown("***Structure of dataset:*** *Each line represents one participant.*"))  
display(Markdown("***Update frequency in UK LLC TRE:*** *Quarterly*"))  
display(Markdown("***Dataset versions in UK LLC TRE:*** *TBC*"))
display(Markdown("***Data quality issues:*** *TBC*"))  
display(Markdown("***Restrictions to data usage***: *Research must be related to COVID-19 and be for medical purposes only (medical research) as defined in the NHS Act 2006: [https://www.legislation.gov.uk/ukpga/2006/41/part/13/crossheading/patient-information](https://www.legislation.gov.uk/ukpga/2006/41/part/13/crossheading/patient-information)*"))  
display(Markdown("***Further information:*** *TBC*"))

NHS England title of dataset: Covid-19 UK Non-hospital Antibody Testing Results

Dataset name in UK LLC TRE: nhsd.IELISA

Short abstract: The Covid-19 UK Non-hospital Antibody Testing Results (Pillar 3) dataset, also referred to as iElisa, documents individuals that have undergone a finger prick test for antibodies from having had Covid-19.

Extended abstract: Also referred to as the Covid-19 UK Non-hospital Antibody Testing Results dataset, IElisa documents individuals who have had a finger prick test for antibodies following a COVID-19 infection (i.e. Pillar 3). The dataset is UK wide and includes demographic and diagnostic information.

Geographical coverage: https://www.geonames.org/2635167/united-kingdom-of-great-britain-and-northern-ireland.html

Temporal coverage: 2020-09-10

Data available in UK LLC TRE from: 01/09/2020 onwards

Typical age range: 0-150

Collection situation: COMMUNITY

Purpose: OTHER

Source: OTHER

Pathway: Not Applicable

Information collected: Demographic and diagnostic information.

Structure of dataset: Each line represents one participant.

Update frequency in UK LLC TRE: Quarterly

Dataset versions in UK LLC TRE: TBC

Data quality issues: TBC

Restrictions to data usage: Research must be related to COVID-19 and be for medical purposes only (medical research) as defined in the NHS Act 2006: https://www.legislation.gov.uk/ukpga/2006/41/part/13/crossheading/patient-information

Further information: TBC

2. Metrics#

The tables below summarise the IELISA dataset in the UK LLC TRE.

Table 1 The number of participants from each LPS that are represented in the IELISA dataset in the UK LLC TRE
(Note: numbers relate to the most recent extract of NHS England data)

gb_cohort = document.get_cohort_count()
print(gb_cohort.to_markdown(index=False, tablefmt="fancy_grid"))
╒════════════════╤═════════╕
│ cohort         │   count │
╞════════════════╪═════════╡
│ ALSPAC         │     108 │
├────────────────┼─────────┤
│ BCS70          │     185 │
├────────────────┼─────────┤
│ BIB            │     276 │
├────────────────┼─────────┤
│ ELSA           │      88 │
├────────────────┼─────────┤
│ EPICN          │      39 │
├────────────────┼─────────┤
│ EXCEED         │     279 │
├────────────────┼─────────┤
│ FENLAND        │     300 │
├────────────────┼─────────┤
│ GLAD           │    3926 │
├────────────────┼─────────┤
│ MCS            │     345 │
├────────────────┼─────────┤
│ NCDS58         │     120 │
├────────────────┼─────────┤
│ NEXTSTEP       │      92 │
├────────────────┼─────────┤
│ NIHRBIO_COPING │    1038 │
├────────────────┼─────────┤
│ NSHD46         │      11 │
├────────────────┼─────────┤
│ TEDS           │     192 │
├────────────────┼─────────┤
│ TRACKC19       │    1177 │
├────────────────┼─────────┤
│ TWINSUK        │     482 │
├────────────────┼─────────┤
│ UKHLS          │     189 │
├────────────────┼─────────┤
│ total          │    8847 │
╘════════════════╧═════════╛

3. Helpful syntax#

Below we will include syntax that may be helpful to other researchers in the UK LLC TRE. For longer scripts, we will include a snippet of the code plus a link to Git where you can find the full script.