COVID-19 Vaccination Adverse Reactions (CVAR) Dataset

COVID-19 Vaccination Adverse Reactions (CVAR) Dataset#

Last modified: 21 Oct 2026

Adverse reactions to vaccinations against SARS-CoV-2 in England.

1. Summary#

Data were collected about people in England who had an adverse reaction to a SARS-CoV-2 vaccination within the first 15 minutes after administration of the vaccine. Data collected include demographic information, vaccination details, vaccine batch details and information about the adverse reaction.

Dataset Descriptor Dataset-specific Information
Name of Dataset in TRE NHSE_CVAR
Citation (APA) Data Services, NHS England (NHSE). (2025). NHS England: COVID-19 Vaccination Adverse Reactions. UK Longitudinal Linkage Collaboration (UK LLC). https://doi.org/10.71760/ukllc-dataset-00381-04
Download Citation Citeproc JSON     BibTeX     RIS
Series NHS England
Owner NHS England
Copyright Copyright © (2026), NHS England. Data re-used with the permission of NHS England. All rights reserved.
Temporal Coverage in the TRE 12/2020 - 01/2023
Geographical Coverage England
Participant Count 74
Number of Variables 33
Number of Observations 154
Key Link https://digital.nhs.uk/services/data-access-request-service-dars/dars-products-and-services/data-set-catalogue/covid-19-vaccination-adverse-reactions
Keywords None
Latest Extract Date 2024-04-26
Specific Restrictions to Data Use Only to be used in research with a focus on COVID-19.
Build a Data Request https://explore.ukllc.ac.uk/

2. Metrics#

Cohort Participant Count
AIRWAVE -1
BCS70 -1
BIB -1
ELSA -1
EPICN -1
EXCEED -1
GLAD 66
MCS -1
NCDS58 -1
NEXTSTEP -1
NIHRBIO_COPING -1
TEDS -1
TRACKC19 -1
TWINSUK -1
UKHLS -1
UKREACH 22

3. Version History#

Version 1 2 4
Version Date 21 Dec 2022 13 Apr 2023 09 Sep 2025
Number of Variables 30 31 33
Number of Observations 98 100 154
DOI 10.71760/ukllc-dataset-00381-01 10.71760/ukllc-dataset-00381-02 10.71760/ukllc-dataset-00381-04
Change Log 10.71760/ukllc-dataset-00381-01/activities 10.71760/ukllc-dataset-00381-02/activities 10.71760/ukllc-dataset-00381-04/activities

4. Documentation#

We are currently building a documentation storage system which will host useful documents related to datasets and data owners. We will surface these documents on Guidebook.

5. Useful Syntax#

Below we will include syntax that may be helpful to other researchers in the UK LLC TRE. For longer scripts, we will include a snippet of the code plus a link to the UK LLC GitHub repository where you can find the full scripts.